Cascara Sagrada (Buckthorn) – Constipation
This is a popular herbal laxative that comes from the bark extract of a species of buckthorn tree. The extracts works by irritating the colon enough to help promote bowel movements. Short-term use is usually well-tolerated, but it may cause abdominal pain or electrolyte imbalance. Long term use may cause liver injury ranging from mild to acute liver failure.